Get a personalised nutrition plan with your DNA

Unlike traditional one-size-fits-all approaches,DNA testing uses insights from your lifestyle and DNA to tailor dietary recommendations that are more likely to support your personal health goals. With accessible at-home DNA tests like MyHealthChecked’s Weight Management DNA Test, these insights are now easier to obtain than ever. By aligning your diet with both your genetic needs and key nutrition principles, you can support overall health while making your meals more purposeful and effective.

The data in our genes

Your genes play a significant role in how your body responds to different foods. This field, known as nutrigenomics, studies how our genes interact with the nutrients in our diet. For example, genetic variations can impact how we process fats, proteins, and carbohydrates, potentially affecting everything from weight management to the risk of chronic diseases like diabetes and heart disease. By understanding these genetic factors, personalised nutrition aims to optimise your diet based on your genetic predisposition, improving health outcomes and possibly reducing disease risks. At-home DNA tests can now reveal these tendencies, offering simple, actionable steps based on your genetic profile.

Genes and your hunger hormones

Genetic variations can also impact how you regulate your hunger. For example, certain variations of the MC4R gene can affect appetite control. Some individuals with these variations may experience more frequent hunger pangs, leading to increased snacking and potential weight management challenges. Conversely, others with different gene variants may have a naturally lower body weight and reduced risk of conditions like Type 2 diabetes and heart disease. Depending on your genetic makeup, you may find certain diets more satisfying or hunger-suppressing.

For those genetically predisposed to heightened snacking tendencies, incorporating a diet rich in healthy snacks and following a Mediterranean diet- abundant in beneficial mono and polyunsaturated fats- can help manage appetite and support weight maintenance. MyHealthChecked’s Weight Management DNA Test analyses genes like MC4R and FTO to provide tailored advice on appetite and eating patterns, helping you make informed food choices.

Eating right for your genes

Protein

Your DNA can reveal whether a high-protein diet could be beneficial for your weight management goals. Individuals carrying a specific gene variant, known as the FTO gene, may experience significant changes in weight management with a high-protein diet. For those genetically suited to a high-protein regimen, increasing protein intake from both animal and plant sources can enhance body composition and facilitate weight loss. Conversely, individuals with a lower genetic predisposition may not experience the same benefits from such a diet.

For those genetically inclined to respond positively to higher protein levels, aiming for a daily protein intake of 1–1.5 grams per kilogram of body weight can help manage appetite and boost energy expenditure, crucial elements for successful weight loss. This is one of the factors explored in the Weight Management DNA Test, which offers protein and macronutrient recommendations based on your DNA.

Vitamin D

DNA tests can also help identify the best dietary sources or supplements to focus on. For instance, genetic variations in the CYP2R1 and GC genes can influence how well your body processes and stores vitamin D, possibly explaining why some people still have low vitamin D levels, despite taking supplements. Individuals with these genetic variants may need to increase their intake of vitamin D-rich foods, get more sunlight exposure, and possibly adjust their supplement dosages based on regular blood tests.

Combining this insight with a blood test, such as MyHealthChecked’s Vitamins & Minerals Profile Blood Test, allows you to understand both your genetic tendency and your current vitamin D levels - helping to guide you on the best steps to take to support your wellbeing.

Iron

If you often feel tired, it might be due to a genetic predisposition to iron deficiency. Iron is essential for important functions like transporting oxygen and producing energy in our bodies. Low iron can lead to anaemia, causing symptoms like fatigue, dizziness, and heart palpitations.

Iron comes in two forms in our diet: haem iron from meat, which is absorbed well, and non-haem iron from plants, which may require vitamin C for better absorption. Genetic factors, especially variations in the transferrin (TF) gene, can affect how iron transports around your body, increasing the risk of deficiency. If you're at risk, focus on eating iron-rich foods alongside vitamin C-rich foods to improve absorption, and avoid consuming dairy and caffeine close to mealtimes as they can interfere with iron uptake.

Again, combining genetic insight with a blood test may help you better manage your iron intake and address tiredness related to iron deficiency.

Nutrition plan motivation

Research from Food4Me reveals that individuals who took part in DNA testing were more likely to eat more fruits and vegetables and follow a stricter nutrition plan. This highlights that customising your diet to include recommendations that align with your genetic profile could not only enhance your awareness of personal health requirements, but also help you to follow healthier eating practices. DNA-based recommendations help simplify decision-making around food and lifestyle changes, especially when paired with clear, practical reports such as those provided by MyHealthChecked.

MyHealthChecked’s Weight Management DNA Test analyses key genes linked to appetite control, carbohydrate response, fat metabolism, protein utilisation, and overall weight management. Your personalised report includes clear, easy-to-follow tips - whether you’re looking to reduce snacking, balance your macronutrient intake, or improve your meal timing and exercise habits. Beyond weight management, the test also explores factors such as your body’s response to carbohydrates, eating behaviours, melatonin levels, impaired weight loss without exercise, and your likelihood of maintaining weight loss long term. These insights can help you take a more informed and sustainable approach to achieving and maintaining a healthy lifestyle.

In summary

While genetic factors play a crucial role in shaping your nutrition plan, it's important to remember that other non-genetic factors such as lifestyle, environment, age, and current health status also significantly influence your nutritional needs and goals. Factors like physical activity levels, stress, sleep patterns, and exposure to pollutants can impact nutritional requirements and effectiveness. Therefore, while DNA tests provide valuable insights, they should not be the sole basis for dietary decisions. Discussing your DNA test results with a healthcare professional, who can consider both your genetic background and current habits, is essential. Combining this information allows for a more comprehensive and effective approach to achieving your nutrition and health goals. The results from MyHealthChecked’s DNA testing services are designed to be practical and easy to apply- providing the foundation for a truly actionable, tailored and healthy nutrition plan.

Reviewed by Dr Dave Nichols

References

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